Submit Manuscript  

Article Details


Protein Kinases as Drug Targets in Human and Animal Diseases

[ Vol. 13 , Issue. 2 ]

Author(s):

Suvarna G. Kini, Vikas Garg, Sharada Prasanna, Revathi Rajappan and Muhammad Mubeen   Pages 99 - 106 ( 8 )

Abstract:


Almost thirty percent of the protein targets currently under exploration and study constitute the protein kinases which have always attracted the pharmaceutical companies as they are easy targets for drug development. Although the kinases will remain major focus of oncology for many years to come in the development of anticancer drugs, the number of kinase inhibitors as therapeutic targets for the treatment of several other diseases which are undergoing clinical trials are exponentially increasing. In this review, we discuss very briefly the different types of protein kinases that have been used as targets for developing drugs for cancer, inflammation, autoimmune disease, heart disease and animal diseases.

Keywords:

Cancer, inflammatory and autoimmune diseases, kinases, protein kinases.

Affiliation:

Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka, Mankind Pharma Research Centre, New Delhi, National Central University, Zhongli District, Taoyuan City, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal-576104, Karnataka

Graphical Abstract:



Read Full-Text article